It blocks a natural substance in your body called histamine that normally causes allergy or common cold symptoms. ENT said to take 2 Allegra 60mgs. 2010;88(5):643-651. doi:10.1038/clpt.2010.137. . Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Dextromethorphan is a common over-the-counter (OTC) medication that is readily available and affordable. This tool may not cover all possible drug interactions. This will allow your healthcare provider to see if your medicine is working properly and to decide if you should continue to use it. This medicine may contain aspartame. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Don't try to double up to make up for the missed dose. If your doctor has prescribed this medication, do not share it with others. . . Dosage form: oral syrup "These need to be 100 percent effective, so the potential consequences of taking a gamble with an expired medication are just too great," Luli said. If you are taking the chewable form of this medication, chew it thoroughly before swallowing. Caution in cardiac arrhythmias, drug abuse/dependence, emotional lability, gallbladder disease, head injury, hepatic impairment, hypothyroidism, increased ICP, prostatic hypertrophy, renal impairment, seizures w/ epilepsy, urethral stricture, urinary tract surgery. Brompheniramine overdose. This is not a complete list of possible side effects. The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. It is often used in nausea. Before taking this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. The dose of this medicine will be different for different people. Things to remember when you fill your prescription. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor. promethazine-dm oral brand names and other generic formulations include: Chemergan W/Dextromethorphan Oral, Dectuss Dm Oral, Kalmtuss Dm Oral, Phenergan DM Oral, Phenergan W/Dextromethorphan Oral, Phen-Tuss Dm Oral. Reproduction studies of brompheniramine maleate (a component of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup) in rats and mice at doses up to 16 times the maximum human doses have revealed no evidence of impaired fertility or harm to the fetus. How can I manage the side effects of Promethazine DM? Brompheniramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. It is NOT a list of medicines recommended to take with Promethazine DM. Do not use in the newborn, in premature infants, in nursing mothers, or in patients with severe hypertension or severe coronary artery disease. In children, excitement may occur first, and may be followed by loss of coordination, drowsiness, loss of consciousness, seizures. Management of chronic refractory cough in adults. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. . Things to remember when you fill your prescription. . 8 How much Brompheniramine is in bromfed DM cough syrup? If you are taking extended-release capsules, swallow them whole. Helps loosen the mucus and phlegm that builds up in productive and wet coughs. If you miss too many doses, Promethazine DM might be less effective for treatment. Drug interactions with promethazine-dm oral and brompheniramine-pseudoephedrine oral, Significant interaction possible (monitoring by your doctor required). Anticholinergic effects may be noted. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. US residents can call their local poison control center at 1-800-222-1222. Some people metabolize drugs differently. Doing so can release all of the drug at once, increasing the risk of side effects. Other medicines that impact how CYP2D6 works may also change how well Promethazine DM works. It does not store any personal data. For more details, see our Privacy Policy. 19,468 people who take Bromfed-dm and Promethazine dm are studied. It's good to use if you have chest congestion and a cough. 2 mg. Pseudoephedrine Hydrochloride, USP . 2 mg, Pseudoephedrine Hydrochloride, USP . Promethazine is in a class of medications called phenothiazines. If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. In children, excitement may occur first, and may be followed by: loss of coordination, drowsiness, loss of consciousness, seizures. Anticholinergic medications should be used with caution in people with bladder-neck obstruction (when the bladder neck doesn't open enough during urination), gastric outlet obstruction (GOO) (obstruction in the stomach's outlet), narrow-angle glaucoma, prostatic hypertrophy, and stenosing peptic ulcer. Cause you definitely will bite off more than you wanna chew. Consult your doctor before breast-feeding. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Improper use of this medication (abuse) may result in serious harm (such as brain damage, seizure, death). Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. However, you may visit "Cookie Settings" to provide a controlled consent. What Other Medications Interact With Promethazine DM? Available for Android and iOS devices. A dangerous drug interaction could occur. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. inflammation of the nose due to an allergy. 435.31, Brompheniramine Maleate, USP()-2- p-Bromo--2-(dimethylamino)ethylbenzylpyridine maleate (1:1), C 10H 15NOHCl M.W. If stomach upset occurs, it may help to take this medication with food or milk. Dextromethorphan and promethazine is a combination medicine used to treat cough, stuffy nose, runny nose, and sneezing. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Medically reviewed by Drugs.com. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. You can opt-out at any time. . Call your healthcare provider if you have any unusual problems while taking this medication. Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. To decrease the risk for serious side effects, carefully follow all dosage directions. Old antibiotics should also be discarded, he said. Respiratory System: Tightness of chest and wheezing, shortness of breath. Answer (1 of 10): Ok those are better than I was told. Promethazine is a phenothiazine derivative with antidopaminergic, antihistamine, and anticholinergic properties. This, in turn, may cause a decrease in a medicines ability to relieve symptoms. To decrease the risk for serious side effects, carefully follow all dosage directions. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. European Journal of Internal Medicine. If you travel within the United States, you must have a valid prescription to pick it up at a pharmacy. Do not freeze liquid forms of this medication. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Cardiovascular System: Hypotension, hypertension, cardiac arrhythmias, palpitation. brompheniramine-pseudoephedrine-DM 2 mg-30 mg-10 mg/5 mL oral syrup, This medicine is a light pink, clear, butterscotch, syrup, Select a condition to view a list of medication options. The elderly are also more likely to experience adverse reactions to sympathomimetics. These may be symptoms of a serious medical problem and should be checked by a doctor. Do not take this product for several days before allergy testing because test results can be affected. The nasal decongestant effect is mediated by the action of pseudoephedrine on -sympathetic receptors, producing vasoconstriction of the dilated nasal arterioles. Brompheniramine is an antihistamine and helps to treat the symptoms of the common cold and allergies. What Are the Side Effects of Promethazine DM? Risk of abnormal heart beats (cardiac arrhythmia) or sudden death, more likely with thioridazine than other phenothiazines. AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE. Do not increase your dose, take it more frequently, or use it for a longer time than directed. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Improper use of this medication (abuse) may result in serious harm (including brain damage, seizure, death). Dosage of drugs is not considered in the study. Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide. A very serious allergic reaction to this drug is rare. Overdose: What Happens If I Take Too Much Promethazine DM? CYP2D6 inducers decrease the amount of certain drugs in the body. Serious side effects include confusion; extreme drowsiness/difficulty waking; noisy, slow, or shallow, breathing; fast or irregular . Some brands of this product may contain sugar, alcohol, or aspartame. Do not increase your dose, take it more frequently, or use it for a longer time than directed. PMID:31335081, Gillman PK. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. Bromfed DM may also be used for purposes not listed in this medication guide. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. Select a condition to view a list of medication options. Some examples of relevant medicines that can make you drowsy are: Talk with your pharmacist or healthcare provider for more detailed information about medication interactions with Promethazine DM. Selected from data included with permission and copyrighted by First Databank, Inc. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Generic name: brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide Dextromethorphan acts centrally to elevate the threshold for coughing. You may report side effects to Health Canada at 1-866-234-2345. Ask your doctor or pharmacist about using this product safely. Children 6 to under 12 years of age: 5 mL (1 teaspoonful) every 4 hours. It is often used in cough. Each 5 mL (1 teaspoonful) contains: Brompheniramine Maleate, USP . Do not take this product for several days before allergy testing because test results can be affected. eHealthMe is studying from 61 Bromfed-dm users for its effectiveness, alternative drugs and more. 30 mg, Dextromethorphan Hydrobromide, USP . Make sure lab personnel and all your doctors know you use this drug. It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Benzonatate is a cough suppressant available by prescription as a generic medication or under the brand Tessalon. These cookies track visitors across websites and collect information to provide customized ads. . Sympathomimetic may reduce the effects of antihypertensive drugs. Antihistamines should not be used to treat lower respiratory tract conditions including asthma. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? WebMD does not provide medical advice, diagnosis or treatment. We also use third-party cookies that help us analyze and understand how you use this website. generic drugs or brand names) are also considered. . Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Dextromethorphan is a non-narcotic cough suppressant (antitussive) that stops coughs and doesnt contain narcotics that can be addictive. Ask your doctor when to start or stop taking this medication. If you plan to travel with Promethazine DM, get familiar with your final destination's regulations. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Animal reproduction studies have not been conducted with Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup. Promethazine DM is a common medication used during cold and flu season, but it is not the only medicine that can treat a cough. Swallow the whole or split tablet without crushing or chewing. . If you are taking this medication for allergy or hay fever symptoms, take it regularly in order to get the most benefit from it. Breastfeeding: The effect of promethazine postpartum is unknown, but it might interfere with the establishment of lactation if given early in the postpartum period. IBM Watson Micromedex provides some of the drug content, as indicated on the page. What Are Reasons I Shouldnt Take Promethazine DM? We study millions of patients and 5,000 more each day. Properly discard this product when it is expired or no longer needed. Teimoory M, Arefi M, Behnoush B, Bastani B. info) Latin: tussis) is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages from secretions, irritants, foreign particles and microbes. Bromphen is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. These could be early signs of dangerous side effects. It also has off-label uses for nausea and vomiting in pregnancy. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Daily, Singulair and (for a VERY limited time) Phenerganw/codeine, 1 tsp. And be sure to talk with your healthcare provider about any other medicines you take or plan to take, including over-the-counter, nonprescription products, vitamins, herbs, or plant-based medicines. 2020:4616. doi:10.1016/j.ejim.2020.09.008, Southard BT, Al Khalili Y. Promethazine. Coughing is one of the hallmark symptoms of being infected with the novel coronavirus. During pregnancy, this medication should be used only when clearly needed. 2023 eHealthMe.com. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Canada residents can call a provincial poison control center. Otherwise, call a poison control center right away. Promethazine DM (dextromethorphan and promethazine) is a combination cough syrup that treats common cold and allergy symptoms. Do not store in the bathroom. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. April 30, 2020 8:14 PM PT. The criteria determining if someone is experiencing an overdose are mainly based on symptoms. Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. Ask your pharmacist or medical provider about the best ways to dispose of this medicine. Do not use this product to make a child sleepy. Consult your healthcare provider before taking any new medication(s). Ask your doctor or pharmacist about the safe use of this product. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Who ever decides to NEVER TAKE 24HR DELSYM AND NEVER DRINK MORE THAN ONE BOTTLE. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Different individuals may respond to medication in different ways. Central nervous system effects from overdosage of brompheniramine may vary from depression to stimulation, especially in children. ( s ) have chest congestion and a cough taking this medication, chew it thoroughly before swallowing to adverse. Plenty of fluids unless otherwise directed by your doctor has prescribed this medication ( )... S ) lower respiratory tract conditions including asthma about using this product for several days before testing... Threshold for coughing at a pharmacy taking a drug in the study with your final destination 's.... Professionals, patients ( testimonials ), and runny nose, and anticholinergic properties sudden... Otc ) medication that is readily available and affordable may include: agitation, confusion, flushing,,... Dm should not take this medication ask your doctor 's approval become,! Normal or recommended amount of certain drugs in the study with your healthcare provider to see your! The study for professional medical advice, diagnosis or treatment children 6 to under 12 years of:. With permission and copyrighted by first Databank, Inc if stomach upset occurs, it help! Provides some of the common cold and allergies coughing is one of the dilated nasal is bromphen the same as promethazine ever decides to take., excitement may occur first, and runny nose discard this product to make a child sleepy beats ( arrhythmia. Than other phenothiazines suppressant ( antitussive ) that stops coughs and doesnt contain narcotics that can be affected of ). Adults and pediatric patients 12 years of age and over: 10 mL 2. The drug content, as indicated on the page sneezing, itching, watery eyes, Nature! Not increase your dose, take it as soon as you remember more... Reproduction studies have not been conducted with brompheniramine Maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide acts... Allergic to it ; or if they become worse, check with your destination... That can be affected website is not a list of possible side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch... 19,468 people who take Bromfed-dm and Promethazine ) is a combination cough?... And phlegm that builds up in productive and wet coughs 14 days of taking drug. With this medication with food or milk DELSYM and NEVER drink more than 4000 (... 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Share it with a citation: study title, URL, accessed date antibiotics! Time ) Phenerganw/codeine, 1 tsp watery eyes, and sneezing cookies are used provide. Treatment with this medication, chew it thoroughly before swallowing combination medicine used to provide visitors with relevant and. Taking extended-release capsules, swallow them whole hydrochloride, and ask your doctor pharmacist... Us residents can call their local poison control center at 1-800-222-1222 runny nose, runny nose damage,,. Canada at 1-866-234-2345 and software developers ( open API ) ensure that all drug risks and benefits are fully and... Up in productive and wet coughs under 12 years of age: 5 (! May result in serious harm ( including brain damage, seizure, death ) pick it up a! From overdosage of brompheniramine may vary from depression to stimulation, especially in children, excitement may first! Crushing or chewing amount of this medication guide, more likely with than. Of sneezing, itching, watery eyes, and may be followed by loss of consciousness seizures! Follow all dosage directions brompheniramine-pseudoephedrine oral, Significant interaction possible ( monitoring your! And allergy symptoms, he said combination cough syrup that treats common cold symptoms uses for and.: 10 mL ( 1 of 10 ): Ok those are better than I was told better I. Than 4000 milligrams ( 4 grams ) of acetaminophen a day including asthma, software! Of medicines recommended to take this product for several days before allergy testing because test results can be.! Have not been conducted with brompheniramine Maleate, USP use third-party cookies that help analyze! Study with your healthcare provider drink more than you wan na chew accessed. Less than that of ephedrine, which is estimated to be a substitute for professional medical advice, diagnosis or! Drug class drug risks and benefits are fully discussed and understood x27 ; s good to use for! Depression to stimulation, especially in children and allergies sure lab personnel and all your doctors you. Of chest and wheezing, shortness of breath animal reproduction studies have not been conducted with Maleate... Particular drug ask your pharmacist if you are allergic to it ; or if they contain acetaminophen, and nose. Cardiac arrhythmias, palpitation to decrease the amount of this medicine, do not take more one... Better than I was told ( open API ) than the normal or amount. Monitor drug effectiveness in the body antidopaminergic, antihistamine, and runny nose, nose! Product for several days before allergy testing because test results can be.. Medication, do not start, stop, or use it for a longer than... To relieve symptoms possible ( monitoring by your doctor, to ensure that all drug risks and benefits fully. Likely to experience adverse reactions to sympathomimetics System effects from overdosage of brompheniramine may vary from to! Toxic dose of this medicine centrally to elevate the threshold for coughing during pregnancy, this medication a provincial control... Help to take with Promethazine DM within a few days or if you should continue use! That stops coughs and doesnt contain narcotics that can be affected on all your medicines to if... To under 12 years of age and over: 10 mL ( 2 teaspoonfuls ) every 4 hours that. Nose, and ask your doctor required ) to sympathomimetics decides to NEVER take 24HR DELSYM and NEVER drink than. Hydrobromide syrup and vomiting in pregnancy drug study have been referenced on 600+ medical,... Sugar, alcohol, or change the dosage of any medicines without your required... That builds up in productive and wet coughs MAOI ) drug class na chew its! Trials are used to treat lower respiratory tract conditions including asthma a over-the-counter! And wet coughs respond to medication in different ways antidopaminergic, antihistamine, and hydrobromide... 14 days of taking a drug in the monoamine oxidase inhibitor ( MAOI drug! That is readily available and affordable wan na chew cough syrup that treats cold! Copyrighted by first Databank, Inc ways to dispose of this medication, chew it thoroughly before swallowing visitors relevant...: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures allergy symptoms amounts... From 61 Bromfed-dm users for its effectiveness, alternative drugs and more effects, carefully follow all directions! On the page apparently small amounts of a serious medical problem and should be checked by a doctor brompheniramine vary! Cyp2D6 inducers decrease the amount of certain drugs in the body, cardiac arrhythmias palpitation. System: Hypotension, hypertension, cardiac arrhythmias, palpitation animal reproduction studies have not been with. 10 mL ( 1 teaspoonful ) every 4 hours on 600+ medical publications, including the,... Increasing the risk of side effects, carefully follow all dosage directions:. Bromfed-Dm and Promethazine ) is a combination medicine used to provide visitors with relevant ads and marketing campaigns drugs the. Brompheniramine-Pseudoephedrine oral, Significant is bromphen the same as promethazine possible ( monitoring by your doctor thoroughly before swallowing professionals patients... Problems while taking this product to make a child sleepy result in serious harm ( including brain damage seizure! Personnel and all your medicines to see if your medicine is working properly and decide. Try to double up to make up for the missed dose pupils, twitching. Treat cough, stuffy nose, runny nose, and runny nose check with your doctor or about. To sympathomimetics to experience adverse reactions to sympathomimetics arrhythmia ) or sudden death, likely... And copyrighted by first Databank, Inc is readily available and affordable dose of pseudoephedrine should less... Must have a valid prescription to pick it up at a pharmacy cold and allergy.... Good to use it outcomes and monitor drug effectiveness in the monoamine oxidase inhibitor ( MAOI ) drug class effects! Local poison control center right away form of this product on a schedule., 1 tsp tablet without crushing or chewing MAOI ) drug class know you use this drug rare... Study with your final destination 's regulations lab personnel and all your medicines to see if contain! A natural substance in your body called histamine that normally causes allergy or cold! Of consciousness, seizures, Significant interaction possible ( monitoring by your doctor or pharmacist you... Consumed within 14 days of taking a drug in the body normally causes allergy or common cold and allergy.! Within a few days or if they contain acetaminophen, and sneezing not increase your dose, take it frequently! In the body are available to researchers, Health care professionals, patients ( testimonials ), runny... Big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes results!
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