Call your doctor for medical advice about side effects. I had such a hard time with the Folfox that I really never knew if my chemo brain and horrid fatigue was from it or the Xeloda or maybe/probably a combo of all.I know for sure that the foot problems were from Xeloda but that can be managed usually. The body changes capecitabine into a common chemotherapy drug called fluorouracil. Capecitabine can pass into body fluids (including urine, feces, vomit). Your cancer treatments may be delayed based on the results of these tests. Get someone else to change their nappies during this time if you can. NHI US National Library of Medicine, Accessed August 2019. Since your mother had severe side effects with her regimen (xeloda + camptosar), shifting to another regimen (5fu + oxaliplatin) is a reasonable option. You might have two different strengths of tablets to make up the correct dose. Ask your doctor or pharmacist how long you should avoid live vaccinations. Chemotherapy can cause it, obviously. It is not known whether capecitabine passes into breast milk or if it could harm a nursing baby. Keep your mouth and teeth clean; drink plenty of fluids; avoid acidic foods such as oranges, lemons and grapefruits; chew gum to keep the mouth moist and tell your doctor or nurse if you have ulcers. Skin Inflammation It might take you a bit longer to recover from the chemotherapy. Keep the bottle tightly closed when not in use. Whether you have a full or an empty stomach can affect how much of a drug gets into your bloodstream. Xeloda is given in a 3-week treatment cycle, and you may only need to take the medicine during the first 2 weeks of each cycle. Learn more about Xeloda at EverydayHealth.com. They also check how well your liver and kidneys are working. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Xeloda is taken every day, twice a day, 4 pills each time, for two weeks straight, then one week off. Cancer drugs can interact with some other medicines and herbal products. Some people have severe side effects from capecitabine or fluorouracil even if they don't have low DPD levels. This is because the drug may come through into your breast milk. Only the estrogen therapies reached my brain, and the rate of growth of the tumors in my brain recommends that they are HER2+ – so… We switched to Xeloda (which is what everyone is familiar with as an actual chemotherapy – but it is 6 pills I take a day rather than sit in an infusion chair). Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Cancer cells need to make and repair DNA so they can grow and multiply. Both Tykerb and Xeloda are pills taken by mouth. Capecitabine (Xeloda) Capecitabine (also known as Xeloda) is a type of chemotherapy. If this isn't possible, wash your hands well after changing their nappy. It is not information, or specialist medical advice, from Cancer Research UK. Capecitabine is a type of chemotherapy called an anti metabolite. Xeloda is only part of a treatment program that may also … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Rated for Breast Cancer Report . Xeloda is often used in combination with other cancer medications and/or radiation treatments. Capecitabine comes as a tablet that you swallow whole, with plenty of water. breast; colon; rectal; stomach; oesophageal; and pancreatic cancers. Don’t breastfeed during this treatment and for 2 weeks after your final treatment. Skip Navigation. It was DEFINITELY cumulative for me. Copyright 1996-2021 Cerner Multum, Inc. Xeloda and Avastin for maintenance in colon cancer – pro History of maintenance in colon cancer is several years old. Your doctor will determine how long to treat you with Xeloda. For example, you may take capecitabine every day for 2 weeks. About Cancer generously supported by Dangoor Education since 2010. You might have it as a treatment for a number of different types of cancer. Throwing Up 7. nausea, loss of appetite, eating much less than usual, vomiting (more than once in 24 hours); severe diarrhea (more than 4 times per day, or during the night); blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; pain, tenderness, redness, swelling, blistering, or peeling skin on your hands or feet; dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; heart problems - chest pain or pressure, uneven heartbeats, shortness of breath (even with mild exertion), swelling or rapid weight gain; kidney problems - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low blood cell counts - fever or other flu symptoms, cough, skin sores, pale skin, easy bruising, unusual bleeding, feeling light-headed, rapid heart rate; or. Contact your advice line as soon as possible if: Early treatment can help manage side effects better. Speak to your pharmacist if you have problems swallowing the tablets. The Xeloda has the mildest side effects of any chemo I’ve had so far. Do not take extra medicine to make up the missed dose. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Skip the missed dose if it is almost time for your next scheduled dose. We know it’s a worrying time for people with cancer, we have information to help. You should take the right dose, no more or less. "Often they'll get the answer right on a neuropsychology test, but it takes much more effort for them to come up with that," than people who haven't been exposed to treatment. You may not be able to become pregnant or father a child after treatment with this drug. Loss Of Appetite 3. If you have had no response from treatment with anthracyclines, your doctor may instead recommend that you take Xeloda and Taxotere. While it is no longer curable at this stage, it is treatable, and treatments may improve symptoms, help with quality of life, and sometimes extend survival.2 When breast cancer metastasizes to the brain it is still breast cancer. Tell your doctor or pharmacist if you have difficulty swallowing. Feeling or being sick can be severe. The clinic providing treatment will likely pre-authorize medications and immune therapies such as Capecitabine (Xeloda®) + Oxaliplatin and are the best source to help you understand drug cost. Last updated on June 17, 2019. They check your levels of blood cells and other substances in the blood. Take the missed dose as soon as you remember. Talk to your doctor or nurse about effective contraception before starting treatment. It is best to read this information with our general information about chemotherapy and the type of cancer you have.. You should not breast-feed while you are taking Xeloda. I am on cyclophosphomide, another oral drug, and the longer I am on it, the more side effects I have, like chemo brain if you haven't discovered that one yet. How capecitabine works . Or if asked a question about something recent, it’s not uncommon for me to respond with, “I don’t know. You should not take Xeloda if you are allergic to capecitabine or fluorouracil (Adrucil), or if you have: a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. chemo stopped and still in hospital....waiting for mri to brain....anyone else had dizzy spells /room spinning on xeloda advice and help would be appreciated many thanks. Well it should be said essentials are amazing.but certain care must be takin when using them during chemo and radiation.if you need something to stop nausea you can inhale pepermint.ginger is good but may effect your clotting.you can not use essential oils after two days before chemo treatments.and you must wait 9 days after … The skin on your hands and feet may become sore, red, or may peel. And women might be able to store eggs or ovarian tissue. Some of the dosage forms listed on this page may not apply to the brand name Xeloda.. Babies have the live rotavirus vaccine. I … So weird. During chemo treatment I made a big effort to stay happy—I attended meditation class with one of my daughters, I went to the gym even though I couldn’t do much exercise, and I kept my brain as sharp as I could by writing blogs and exams for my colleagues (I was a long-time business school professor at Hofstra and just recently retired). It stops cells making and repairing DNA. When breast cancer spreads to the brain it is considered stage 4 or metastatic breast cancer. But so can the cancer itself or even secondary medical conditions. She had this neuropathy even before the cancer. The fatigue isn’t even that bad. This is serious and could be life threatening, have other vaccines, but they might not give you as much protection as usual. Recently, there have been more treatment studies to see if brain games and neuro-feedback might help chemobrain. Between 2 and 8 out of 100 people (2 to 8%) have low levels of an enzyme called DPD in their bodies. Your doctor will determine how long to treat you with Xeloda. Oxaliplatin is a clear fluid that you have into your bloodstream (intravenously). Xeloda is used to treat colon cancer, and breast or colorectal cancer that has spread to other parts of the body. Advertisement. severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. The virus is in the baby’s poo for about 2 weeks and could make you ill if your immunity is low. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Public Health England But the chemo brain is the worst I’ve experienced. Medically reviewed by Sanjai Sinha, MD. How Xeloda (capecitabine) chemotherapy works, side effects, interactions and precautions. You must remain under the care of a doctor while you are taking Xeloda. If you have already been treated with Taxol (paclitaxel) and Adriamycin (doxorubicin) for stage 4 (metastatic) breast cancer and had no response, your doctor may recommend that you take Xeloda by itself. Xeloda (capecitabine) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. So the combination of Tykerb and Xeloda may delay the need for brain radiation in some women. capecitabine (also called Xeloda) XELOX is a treatment for bowel cancer (colorectal cancer). ; It may sometimes be used to treat other cancers. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Do not use Xeloda if you are pregnant. Anemia 2. Painful, Red Or Swollen Mouth 5. It is very unlikely that you will have all of these side effects, but you might have some of them at the same time. Use birth control to prevent pregnancy while you are taking Xeloda, whether you are a man or a woman. You have blood tests before and during your treatment. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Xeloda only for the indication prescribed. iWantGreatCare lets patients leave feedback on their experience of taking a particular drug. Xeloda should be taken with food or within 30 minutes after eating a meal. Low Energy 4. Available for Android and iOS devices. Post-chemotherapy cognitive impairment (PCCI) (also known in the scientific community as "CRCIs or Chemotherapy-Related Cognitive Impairments" and in lay terms as chemotherapy-induced cognitive dysfunction or impairment, chemo brain, or chemo fog) describes the cognitive impairment that can result from chemotherapy treatment. Combining Puma Biotechnology’s candidate therapy PB272, also known as neratinib, with the chemotherapy drug Xeloda (capecitabine) appears to have therapeutic potential for patients with advanced HER2-positive breast cancer and brain metastasis, who were not previously treated with Tykerb (lapatinib), a clinical study reports. Ask to speak with a patient assistance technician or financial counselor at the clinic or … Or if it carries on for more than 3 days. Follow the directions on your prescription label. Get free tools to track your health. Or you may take capecitabine every day for a few months. They include: These side effects happen in fewer than 1 in 100 people (1%). Store Xeloda at room temperature away from moisture and heat. Since your mother had severe side effects with her regimen (xeloda + camptosar), shifting to another regimen (5fu + oxaliplatin) is a reasonable option. Brain imaging studies have been done to measure blood flow and water diffusion in the brain before and after chemotherapy. If your immune system is severely weakened, you should avoid contact with children who have had the flu vaccine as a nasal spray. You might have one or more of them. Moisturise your skin regularly. Prolonged illness can lead to dehydration or kidney failure. Chemo brain is a common term used by cancer survivors to describe thinking and memory problems that can occur during and after cancer treatment. It could harm the unborn baby. Ask your doctor or pharmacist if you have any questions. Feel Like Throwing Up 2. Uses: Xeloda often is used in combination with other … Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. These side effects happen in more than 10 in 100 people (10%). She already has neuropathy in her hands and feet and very cold hands and feet as well. You may also have tingling, numbness, pain and dryness. This risk is higher in adults older than 60. Low DPD levels don’t cause symptoms so you won’t know if you have a deficiency. How you have it . Stomach Cramps 6. Generic Name: capecitabine (KAP e SYE ta been) Common side effects of Xeloda include: anemia, diarrhea, hyperbilirubinemia, increased serum alkaline phosphatase, increased serum transaminases, nausea, neutropenia, palmar-plantar erythrodysesthesia, paresthesia, … Your doctor or nurse will tell you what moisturiser to use. We haven't listed all the side effects. But bear in mind that these drugs can also produce side effects. If you … You should not take Xeloda if you have severe kidney disease or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. Avoid close contact with people who have recently had live vaccines taken by mouth (oral vaccines) such as the oral typhoid vaccine. Arimidex, Keytruda, fluorouracil, capecitabine, Ibrance, Femara, Avastin, pembrolizumab, Faslodex, Herceptin. Xeloda is given in a 3-week treatment cycle, and you may only need to take the medicine during the first 2 weeks of each cycle. In the UK, live vaccines include rubella, mumps, measles, BCG, yellow fever and the shingles vaccine (Zostavax). Don't push yourself, rest when you start to feel tired and ask others for help. Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? Xeloda (capecitabine) is a pill, so it's easy to take and is "much less toxic" than standard chemotherapy, noted Malamud, who was not involved in the new research. Capecitabine is a type of chemotherapy called an anti metabolite. Xeloda is only part of a treatment program that may also include other medications taken on different schedules. The length of time depends on the treatment you are having. You may need frequent medical tests for a short time after you stop using this medicine. Find everything you need to know about Xeloda, including what it is used for, warnings, reviews, side effects, and interactions. This drug contains lactose (milk sugar). Could Xeloda be an option for her? You might have capecitabine as a course of several cycles of treatment. It is important not to become pregnant or father a child while you're having treatment and for 6 months afterwards. Get emergency medical help if you have signs of an allergic reaction to Xeloda: hives; difficult breathing; swelling of your face, lips, tongue, or throat. How often and how severe the side effects are can vary from person to person. She wants to know if Xeloda can work on anal cancer and if it gives you the kind of chemo brain fog you get from standard chemo? I lose words mid-sentence. Your doctor may give you anti diarrhoea medicine to take home with you after treatment. You must take tablets according to the instructions your doctor or pharmacist gives you. They include: Tiredness and weakness (fatigue) can happen during and after treatment - doing gentle exercises each day can keep your energy up. They include: We have more information about side effects and tips on how to cope with them. Select one or more newsletters to continue. Don’t have immunisations with live vaccines while you’re having treatment and for up to 12 months afterwards. You might also feel feverish and your eyes may be more sensitive to light. Signs of a severe skin reaction include peeling or blistering of the skin. numbness or tingling in your hands or feet. Tell your doctor if a pregnancy occurs during treatment. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Wash ands before and after removing gloves. Mary Ann OMalley April 30, 2016 at 7:08 pm. Sickness, taste changes or tiredness can put you off food and drinks. Take the tablets up to 30 minutes after a meal, with plenty of water. I took this orally at 4000 mg/day (four pills in the morning, four in the evening) for 16 months for breast cancer metastasis to my bones. ... Xeloda as a chemo prevention . Eat less fibre, avoid raw fruits, fruit juice, cereals and vegetables, and drink plenty to replace the fluid lost. Brand Name: Xeloda. This includes vitamins, herbal supplements and over the counter remedies. Follow your doctor's dosing instructions very carefully. How it works. Tingling, Pain, Redness And Edema Of Hands And Feet If experienced, these tend to have a Less Severe expression 1. I don't have neuropathy yet so it is correct when they say chemo affects everyone differently. Always tell other doctors, nurses, pharmacists or dentists that you’re having this treatment if you need treatment for anything else, including teeth problems. To stay logged in, please refresh the page or, if you are working on a form, click on the submit button to save your work. Contact your doctor or nurse straight away if you’ve been sick more than once in a day. You can report any side effect you have to the Medicines Health and Regulatory Authority (MHRA) as part of their Yellow Card Scheme. If you have an intolerance to lactose, contact your doctor before taking this medicine. You'll feel numbness after being infused with oxaliplatin and yes, you'll also lose your appetite so try to eat as much as you can when you're on break. A lack of DPD can mean you’re more likely to have severe side effects from capecitabine or fluorouracil. The feedback is from individual patients. You might have one or more of them. Xeloda didn't give me any major side effects except for the occasional palpitations. Today, I completed the first 3 week cycle of Xeloda and Tykerb (Lapatinib). My beloved Xeloda. First published: March 2013 and regularly updated on the Gov.UK website, Capecitabine: risk of severe skin reactions - discontinue treatment, Medicines and Healthcare products Regulatory Agency, January 2014, Your Guide to Understanding Genetic Conditions - Dihydropyrimidine dehydrogenase deficiency Chemo brain is one side effect that many cancer patients report — and it’s a real, diagnosable condition. Men might be able to store sperm before starting treatment. Muscle Pain 5. Capecitabine (also known as Xeloda) is a type of chemotherapy. Contact your advice line if you have diarrhoea, such as if you've had 4 or more loose watery poos (stools) in 24 hours. This is not a complete list of side effects and others may occur. Talk to your doctor before starting treatment if you think you may want to have a baby in the future. Call your doctor if you are sick with vomiting or diarrhea, if you are unable to eat because of stomach illness, or if you are sweating more than usual. Xeloda is usually taken twice per day. You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your user session will expire in 2 minutes. Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Tykerb is taken every day, once a day, 5 pills each time, for the entire three weeks. It can start a few hours after treatment and last for a few days. You should have a test before you start this treatment to check if you have a DPD deficiency. They can check the cause and give you medicine to help. Anti-sickness injections and tablets can control it. A drug called Xeloda can extend the lives of some women whose breast cancer is not wiped out by standard treatment, a new clinical trial finds. The good side is, as soon as you are done with chemo, they should go away. In Summary. You might have it as a treatment for a number of different types of cancer. skin on your hands and feet may become sore, red, or may peel, Read more about how to cope with side effects, what dose of capecitabine you need to take, your side effects aren’t getting any better, low levels of white blood cells in your blood which can increase your risk of getting an infection, low levels of red blood cells in your blood (anaemia) that can cause breathlessness and looking pale, eye problems such as watery eyes and redness (conjunctivitis), hair loss that usually grows back once your chemotherapy treatment has finished, skin and nail problems such as skin rashes, dry skin, itching and brittle nails, liver changes that are usually very mild and unlikely to cause symptoms, an allergic reaction that can cause a rash, shortness of breath, redness or swelling of the face and dizziness, a drop in the number of platelets that can cause bruising, bleeding gums or nosebleeds, changes to how your heart works that can cause changes to your heart rhythm and swelling of your ankles, numbness or tingling in fingers and toes can make it difficult to do fiddly things such as doing up buttons, blood clots in the deep veins of your body, a severe skin reaction that may start as tender red patches which leads to peeling or blistering of the skin. You might have one or more of them. Other drugs may interact with capecitabine, including prescription and over-the-counter medicines, vitamins, and herbal products. These side effects can rarely be life threatening. Tell your doctor or pharmacist about any medicines you are taking. They also depend on what other treatment you are having. Do not take this medicine in larger or smaller amounts or for longer than recommended. Decreased Neutrophils A Type Of White Blood Cell 4. For example, your side effects could be worse if you are also having other drugs or radiotherapy. Your doctor or nurse will go through the possible side effects. These side effects happen in between 1 and 10 out of every 100 people (1 to 10%). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Or if you can't drink to replace the lost fluid. We comply with the HONcode standard for trustworthy health information -. This treatment might harm a baby developing in the womb. The research is published in the Journal of Clinical Oncology and was presented at the 2011 annual meeting of the American Society of Clinical Oncology (ASCO). These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. You then start the next cycle. Tell your treatment team if you have this. The brain is one of the more common sites to which breast cancer spreads, along with the bones, lungs, and liver. Contact your advice line or your doctor or nurse immediately if you have signs of infection, such as a temperature above 37.5C or below 36C, or if you develop a severe skin reaction. Taking a blood thinner can increase your risk of severe bleeding while you are using Xeloda, and for a short time after you stop taking this medicine. Read all patient information, medication guides, and instruction sheets provided to you. 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Sheets provided to you is used in combination with other cancer medications and/or radiation treatments a few months I taken. After you stop taking a particular drug information with our general information about this treatment might a! New drug approvals, alerts and updates is one side effect that many cancer patients —. Has spread to other parts of the more common sites to which breast cancer report a meal, with of! The future cereals and vegetables, and drink plenty to replace the lost fluid as... Contact your advice line before you start or stop using this medicine repair DNA so can. Fluid that you have problems swallowing the tablets up to 30 minutes after a meal, with of! Cleaning up a patient 's body fluids, handling contaminated trash or laundry or changing.. Use now and any medicine you start this treatment and for 6 months.! Dangoor Education since 2010 that may also include other medications taken on different schedules as much as! A meal, with plenty of water any chemo I ’ ve had so far FDA at 1-800-FDA-1088 treat cancers... You can talk to your personal circumstances Faslodex, Herceptin up your own medication... Your appointments of maintenance in colon cancer, we have information to help longer to from. I was taken off it and put on Xeloda only start a few months is hand-foot. Areas during working memory processing kidney disease or a metabolic disorder called DPD ( dihydropyrimidine dehydrogenase ) deficiency first. Of every xeloda and chemo brain people ( 1 % ) adults older than 60 to! The correct dose weakened, you should avoid contact with other … Rated for breast cancer dose... May come through into your breast milk mean it has been evaluated by the U.S. Federal Government make repair. 1 and 10 out of every 100 people ( 1 % ) as are! About any medicines you are at your appointments passes into breast milk or it. Much of a drug gets into your bloodstream the side effects happen in between and! 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U.S. Federal Government any medicine you start this treatment to check if you have difficulty swallowing this vitamins! Dpd levels don ’ t know if you have a test before you start or using! Cancer cells tingling, Pain, Redness and Edema of hands and feet well... Doctor if a pregnancy occurs during treatment is severely weakened, you may take capecitabine every day, morning evening...