The use of laboratory animals in Malaysia (or Malaya as it was called then) began in the early 1900s when the Institute for Medical Research (IMR) was established in Kuala Lumpur by the British colonial government. The AWA became the first Federal law protecting the welfare of laboratory animals and brought the issue of stolen pets to the forefront of animal welfare concerns. • 21 CFR Part 58 Good Laboratory Practices For Nonclinical Studies • The proposed regulations for Good Laboratory Practice were published in the Federal Register on November 19, 1976. Submitted aplllications first to the local Person with Special Control Responsibility (PMSK) for quality check. Breeding of and Experiments on Animals (Control and Supervision) Rules, 2006 45 -48 6. Introduction to Animal Cell Culture : Animal cell culture basically involves the in vitro (in the laboratory) maintenance and propagation of animal cells in […] Key Changes in the 2010 Guide for the Care and Use of Laboratory Animals Handling of laboratory animals and ethics 10th to 11th Novomber, 2016 Laboratory Animal Resources Section ICAR- Indian Veterinary Research Institute Izatnagar, Bareilly-243 122(U.P), India Training Program on US Department of Agriculture (USDA) Regulations This is the full text of the animal welfare regulations promulgated by the USDA to implement the Animal Welfare Act. The PCA Act, 1960 has also established the Animal Welfare Board of India and the Committee for the purpose of Control and Supervision of Experiments on Directive 2010/63/EU Directive 2010/63/EU revising Directive 86/609/EEC on the protection of animals used for scientific purposes was adopted on 22 September 2010. Laboratory Animal Regulation and Administration System in China. Rules and Regulations of this act were amended in 1998 and 2001. Minimum training levels are listed by laboratory position in Appendix 1, Personnel Qualifications.” 2.2 Finance and Budget Toxicity testing in laboratory animals provides much of the information needed to characterize the nature and extent of the risk so that appropriate risk-management action can be taken. The use of laboratory animals is one of the most regulated uses of animals in the United States, and other countries as well. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. All over the world, animal models are used in pre-clinical research to learn more about how the body works, and to identify causes and develop treatments and cures for disorders and diseases. Experimental summaries must satisfy the requirements according to the regulation (see below), documentation of training is checked and the Animal Welfare Body give input on the 3Rs. See our Privacy Policy and User Agreement for details. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Breeding of and Experiments on Animals (Control and Supervision) Rules, 2001 42 -44 5. This content applies to human and veterinary medicines. The Italian animal welfare and veterinary health rules and regulations (law n. 116/1992 and derived laws and decrees, in application of EU guideline 86/609/EEC) concerning the care and utilization of laboratory animals, require the following: 1) License for breeding, importation and exportation of laboratory animals. It also requires the use of anesthesia or analgesic drugs for potentially painful procedures and during post-operative care. (2006) Different laboratory animals and their applications, Practical in pharmacology, B.S.Shah prakashan,6:7- … Dr. Sindhu K., Asst. Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell), No public clipboards found for this slide. See our Privacy Policy and User Agreement for details. The use of laboratory animals is governed by an interrelated, dynamic system of regulations, policies, guidelines, and procedures. No public clipboards found for this slide, Student at Chalapathi Institute of Pharmaceutical Sciences, Lam. (committee for the purpose of control and supervision on experiments on animal). The Animal Welfare Act, or AWA, is a federal law that addresses the standard of care animals receive at research facilities. The scope is now wider and includes foetuses of mammalian species in their last trimester of development and cephalopods, as well as animals used for the purposes of basic research, higher educ… Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. ), shall receive appropriate identification. FACILITY If you continue browsing the site, you agree to the use of cookies on this website. See our User Agreement and Privacy Policy. • 21 CFR Part 58 Good Laboratory Practices For Nonclinical Studies • The proposed regulations for Good Laboratory Practice were published in the Federal Register on November 19, 1976. HANDLING. Looks like you’ve clipped this slide to already. CPCSEA GUIDELINES FOR Howard B, Nevalainen T, Perretta G). | PowerPoint PPT presentation | free to view 1. SEMISTER) screening of laboratory animals to identify asymptomatic infections (Johnson, 2011). What to Upload to SlideShare SlideShare. Together, Duke’s Institutional Animal Care and Use Committee (IACUC) and Division of Laboratory Animal Resources (DLAR), maintain a program which assures compliance with the Animal Welfare Regulations The Directive is firmly based on the principle of the Three Rs, to replace, reduce and refine the use of animals used for scientific purposes. of VPT, VCG. Executive Guideline No. Cpcsea guidelines for laboratory animal facility. • Congress proposed and enacted the Good Laboratory Practice Regulations for FDA as part of the Federal Food, Drug, and Cosmetic Act (FD&C). Webinar On Good Laboratory Practice Regulations - This webinar is a must for those personnel that require an understanding of the regulations governing laboratory activities relative to nonclinical testing that support or are intended to support applications for products regulated by FDA. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research. PHARMACY Animal experiments can only be performed if there is an ethical permit/ethical license which is granted by an ethical committee. If you continue browsing the site, you agree to the use of cookies on this website. Comparison of FDA, EPA, OECD GLP In: The COST Manual of Laboratory Animal Care and Use, Refinement, Reduction and Research (Eds. The Italian animal welfare and veterinary health rules and regulations (law n. 116/1992 and derived laws and decrees, in application of EU guideline 86/609/EEC) concerning the care and utilization of laboratory animals, require the following: 1) License for breeding, importation and exportation of laboratory animals. REFERENCES 55 (1) Committee for the purpose of control and supervision on experiments on animals, CPCSEA guidelines for laboratory animal facilities, Chennai: 3-36. Guidelines on the Regulation of Scientific Experiments on Animals 49 -60 7. The principles of Good Laboratory Practice (GLP) define a set of rules and criteria for a quality system concerned with the organisational process and the conditions under which non-clinical health and environmental safety studies are planned, performed, monitored, recorded, reported and archived. Other laws, policies, and guidelines may include additional species coverage or specifications for animal care and use, but all refer to the Animal Welfare Act as the minimum acceptable standard. The GLP regulations are found in 21 CFR Part 58.1: Good Laboratory Practice for Nonclinical Laboratory Studies. 2) Goyel R K., et al. Laboratory Safety Rules, Procedures and Regulations Safety Rules Ensuring laboratory safety is not just the responsibility of the instructor; it is the responsibility of everyone working in the laboratory. Regulations for the Management of Laboratory Animals at Fujita Health University . TOXICITY TESTING. Handling of laboratory animals and ethics 10th to 11th Novomber, 2016 Laboratory Animal Resources Section ICAR- Indian Veterinary Research Institute Izatnagar, Bareilly-243 122(U.P), India Training Program on If you continue browsing the site, you agree to the use of cookies on this website. Dr. Sindhu K., Asst. If you continue browsing the site, you agree to the use of cookies on this website. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Cpcsea guidelines for laboratory animal facility. Bioassay techniques Dr. Sindhu K., Asst. Food and Drugs Administration (FDA) List of FDA inspections of facilities that perform nonclinical laboratory studies. Prof., Dept. 21, 11-11-83; Revised 7-6-16. laboratory animals according to the animal welfare and ethical norms. Baumans V, Augustsson H, Perretta G (2010) Animal needs and environmental refinement. ADVERTISEMENTS: Read this article to learn about the fundamentals, facilities, aseptic conditions, advantages, disadvantages of animal cell culture and also about the risks & safety regulations in a tissue culture laboratory. By Javier Guillen (Editor) Record number: 68921 This book is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. On the other hand, some species of laboratory animals are susceptible to diseases transmitted by humans (e.g. The Animal Welfare Act was signed into law in 1966. Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. Subsequent laws have placed regulations and restrictions on the use of draught animals, use of performing animals, animal transport, animal slaughter, and animal experimentation. PRESENTED BY: S.S.CHAUDHARI The federal Food, Drug, and Cosmetic Act requires the Food and Drug Administration (FDA), under the DHHS, to ensure proper procedures for the care and use of laboratory animals, as implemented by the Good Laboratory Practice (GLP) regulations (21 CFR, Part 58) that became effective June 1979 and were most recently amended in 2002 . Posted on 6/24/2019. Purpose - This Executive Guideline is intended to provide general direction for the development and maintenance of an Occupational Health and Safety Program (OHSP) tailored to the needs of persons whose employment involves contact with laboratory animals and/or animal tissue. Ethical evaluation of animal experiments Experiments conducted under a license should be kept in an animal record. Control and Supervision of Experiments on Animals’ (CPCSEA) and framed the Rules and Regulations for implementation of the Act. In the U.S., the federal Animal Welfare Act (AWA) and the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy) regulate the use of laboratory animals. 2.1.2 The laboratory personnel shall be able to provide competence in all management and technical groups evaluated for accreditation. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Amendments to the AWA enacted in 1970, 1976, 1985, 1990, and 2002 refined standards of care and extended coverage to animals in commerce, exhibition, teaching, testing, and research. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Now customize the name of a clipboard to store your clips. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. of VPT, VCG. laboratory animal diagnostic laboratories supported by the National Institutes of Health. CPCSEA GUIDELINES FOR LABORATORY ANIMAL The use of animals in experiments and testing is regulated under the Animals (Scientific Procedures) Act 1986 (ASPA) adopting the principles of the 3Rs(Replacement, Reduction and Refinement). DEPARTMENT OF PHARMACOLOGY You are expected to be familiar with the safety rules and to conduct your laboratory work in a safe manner at all times. • Congress proposed and enacted the Good Laboratory Practice Regulations for FDA as part of the Federal Food, Drug, and Cosmetic Act (FD&C). ILAR Journal 46: 162-170. CPCSEA Guidelines for Laboratory Animal Facility - 2015 61 … Customer Code: Creating a Company Customers Love HubSpot. ASPAis implemented by the Home Office in England, Scotland and Wales and by the Department for Health, Social Security and Public Safety in Northern Ireland. You can change your ad preferences anytime. The Institute’s main function was the study of tropical diseases, and laboratory animals were used as animal models. The Guide takes into consideration regulatory requirements relevant to many US-based activities, including the Animal Welfare Regulations (USDA 1985; US Code, 42 USC § 289d) and the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS 2002). See our User Agreement and Privacy Policy. By Javier Guillen (Editor) Record number: 68921 This book is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. In: Enrichment Strategies for Laboratory Animals. R C PATEL COLLEGE OF Now customize the name of a clipboard to store your clips. Use of Laboratory Animals INTRODUCTION PURPOSE Proper care and use of laboratory animals is not only the humane thing to do, it is the law. National Research Council Institute for Laboratory Animal Research Committee on Guidelines for the Humane Transportation of Laboratory Animals (2006). It is the only Federal law in the United States that regulates the treatment of animals in research, exhibition, transport, and by dealers. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. CPCSEA GUIDELINE FOR LABORATORY ANIMAL CARE AND HANDLING..... Looks like you’ve clipped this slide to already. April 1, 2007 (Preface) Conducting life science research animal experiments that involvesat the University is required not only for the development and deployment of improved health, welfare, and advanced medicine, but also for the of the advancement 1. 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